SCIENTIFIC PUBLICATIONS AND POSTERS

Home » Resources / Publications and Posters

Poster: Identification of Specific EEG Biomarkers in Aged Mice

This new analysis pipeline provides a tool to more quickly and objectively assess the effects of compounds in development and compare them to existing reference drugs for various indications.

Poster: Standardized Pharmaco-Sleep-Electroencephalography as a Preclinical Tool for Antidepressant Drug Profiling

We evaluated the possibility to employ a Machine Learning approach to assess the dose-dependency of antidepressants, with distinct mechanisms of action: fluoxetine and maprotiline in wild-type C57BL/6 mice.

Poster: Assessing Sleep Architecture and Pharmacodynamics: An EEG-Based Platform for Drug Testing

This new analysis pipeline provides a tool to more quickly and objectively assess the effects of compounds in development and compare them to existing reference drugs for various indications.

Publication: Differential Effects of Antiepileptic Drugs on Focal Seizures in the Intrahippocampal Kainate Mouse Model of Mesial Temporal Lobe Epilepsy

Focal Epilepsy

Publication: Pronounced Antiepileptic Activity of the Subtype-Selective GABAA -Positive Allosteric Modulator PF-06372865 in the GAERS Absence Epilepsy Model

Generalized Absence Epilepsy.
A joint publication SynapCell x Pfizer.

Publication: BAER-101, a selective potentiator of α2- and α3-containing GABAA receptors, fully suppresses spontaneous cortical spike-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg (GAERS)

Generalized Absence Epilepsy.

Poster: Evaluating QEEG and Phase Amplitude Coupling as a Direct Window on Brain Function, a Preclinical Study

In this poster, we identify functional signatures in mice using qEEG and related methodologies (Phase Amplitude Coupling and cPAC).

Poster: Decoding Therapeutic Signatures: The Contribution of Pharmaco-EEG in Profiling Compounds with Varied Mechanisms of Action

The goal: Defining the potential specific signature associated with a therapeutic class of compounds.

Poster: Pronounced Antiepileptic Activity of the Subtype-Selective GABAA Positive Alosteric Modulator PF-06372865 in the GAERS Model

Assessing the antiepileptic effect of PF-06372865, a newly developed GABAA modulator, developed by Pfizer, in a preclinical model of absence seizures, the GAERS rat.