SCIENTIFIC PUBLICATIONS
AND POSTERS
POSTER
Sleep and Vigilance States
Standardized Pharmaco-Sleep-Electroencephalography as a Preclinical Tool for Antidepressant Drug Profiling
In this study, we hypothesized that drug effects may be expressed differently depending on vigilance states (VS) during recording sessions. We used automatic state-detection (Machine Learning approach) as a tool to estimate VS-specific effects of drugs. We evaluated the usefulness of this method in wild-type C57BL/6J mice with a study assessing the dose-dependency of antidepressants with distinct mechanisms of action: fluoxetine and maprotiline.
– This poster will be presented at the SfN Neuroscience 2024 conference and will be available for download after the event. Thank you for your understanding –
