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Identification of Specific EEG Biomarkers in Aged Mice
The current challenge in neurodegenerative disease research is the identification of reliable biomarkers for early diagnosis, as existing methods often detect the disease only after significant neurological damage has occurred. Aging is a well-known risk factor for pathologies such as Parkinson’s disease, Alzheimer’s disease, and cognitive impairment. It leads to deep changes in the brain such as a shrinking of the cortex, loss of brain plasticity, and reduced neuroplasticity of brain circuits. We have attempted to identify specific biomarkers to predict an upcoming decline in brain function.
In this work we took advantage of electroencephalography and related technologies to:
– Physiologically and functionally characterise aged mice a using quantitative electroencephalography (qEEG).
– Evaluate the impact of aging on the ability to process sensory (auditory) information.
– This poster will be presented at the SfN Neuroscience 2024 conference and will be available for download after the event. Thank you for your understanding –
