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Sleep and Vigilance States

Sleep Architecture and Pharmacodynamics: An EEG-Based Platform for Drug Testing

In this study, we develop an analysis pipeline based on an in-house EEG platform focused on sleep architecture to test how drugs affect vigilance states (i.e. wakefulness, rapid eye movement (REM) sleep and non-rapid eye movement (NREM) sleep) as reflected by the corresponding pharmacodynamic modulations of frequency bands. This new analysis pipeline provides a tool to more quickly and objectively assess the effects of compounds in development and compare them to reference drugs for various indications.

– This poster will be presented at the SfN Neuroscience 2024 conference and will be available for download after the event. Thank you for your understanding –

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